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Airway Bacteria Quantification Using Polymerase Chain Reaction Combined with Neutrophil and Eosinophil Counts Identifies Distinct COPD Endotypes
Background: Chronic obstructive pulmonary disease (COPD) inflammatory endotypes are associated with different airway microbiomes. We used quantitative polymerase chain reaction (qPCR) analysis of sputum samples to establish the bacterial load upper limit in healthy controls; these values determined...
Autores principales: | Beech, Augusta, Lea, Simon, Li, Jian, Jackson, Natalie, Mulvanny, Alex, Singh, Dave |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533560/ https://www.ncbi.nlm.nih.gov/pubmed/34680454 http://dx.doi.org/10.3390/biomedicines9101337 |
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