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Heat Shock Cognate 70 kDa Protein Is the Target of Tetradecyl 2,3-Dihydroxybenzoate for Neuritogenic Effect in PC12 Cells

Tetradecyl 2,3-dihydroxybenzoate (ABG-001) is a lead compound derived from gentisides with a remarkable neuritogenic activity. However, the target of ABG-001 is yet to be defined to date. In this study, the potential target of ABG-001 was investigated via an activity-based protein profiling (ABPP) a...

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Detalles Bibliográficos
Autores principales: Cheng, Lihong, Wang, Yanhui, Xiang, Lan, Qi, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533567/
https://www.ncbi.nlm.nih.gov/pubmed/34680600
http://dx.doi.org/10.3390/biomedicines9101483