Inhibition of Membrane-Associated Catalase, Extracellular ROS/RNS Signaling and Aquaporin/H(2)O(2)-Mediated Intracellular Glutathione Depletion Cooperate during Apoptosis Induction in the Human Gastric Carcinoma Cell Line MKN-45

The human gastric carcinoma cell line MKN-45 is a prototype of bona fide tumor cells, as it is protected from the NADPH oxidase-1 (NOX-1)-driven HOCl- and nitric oxide (NO)/peroxynitrite apoptosis-inducing signaling pathways by a membrane-associated catalase. The use of inhibitors/scavengers shows t...

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Detalles Bibliográficos
Autor principal: Bauer, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533628/
https://www.ncbi.nlm.nih.gov/pubmed/34679719
http://dx.doi.org/10.3390/antiox10101585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533628/
https://www.ncbi.nlm.nih.gov/pubmed/34679719
http://dx.doi.org/10.3390/antiox10101585

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