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Interferon-γ Produced by EBV-Positive Neoplastic NK-Cells Induces Differentiation into Macrophages and Procoagulant Activity of Monocytes, Which Leads to HLH

SIMPLE SUMMARY: Epstein–Barr virus (EBV), a common virus all over the world, infects not only B-cells but also T- and NK-cells. Once infected with EBV, human beings remain infected for life, and EBV renders infected B-cells immortal. EBV-positive NK-cell neoplasms, such as extranodal NK/T-cell lymph...

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Detalles Bibliográficos
Autores principales: Yoshimori, Mayumi, Nishio, Miwako, Ohashi, Ayaka, Tateishi, Megumi, Mimura, Ayaka, Wada, Naomi, Saito, Minori, Shimizu, Norio, Imadome, Ken-Ichi, Arai, Ayako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533691/
https://www.ncbi.nlm.nih.gov/pubmed/34680246
http://dx.doi.org/10.3390/cancers13205097