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Targeting Notch to Maximize Chemotherapeutic Benefits: Rationale, Advanced Strategies, and Future Perspectives

SIMPLE SUMMARY: The Notch signaling pathway regulates cell proliferation, apoptosis, stem cell self-renewal, and differentiation in a context-dependent fashion both during embryonic development and in adult tissue homeostasis. Consistent with its pleiotropic physiological role, unproper activation o...

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Detalles Bibliográficos
Autores principales: Zhdanovskaya, Nadezda, Firrincieli, Mariarosaria, Lazzari, Sara, Pace, Eleonora, Scribani Rossi, Pietro, Felli, Maria Pia, Talora, Claudio, Screpanti, Isabella, Palermo, Rocco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533696/
https://www.ncbi.nlm.nih.gov/pubmed/34680255
http://dx.doi.org/10.3390/cancers13205106