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Targeting Notch to Maximize Chemotherapeutic Benefits: Rationale, Advanced Strategies, and Future Perspectives

SIMPLE SUMMARY: The Notch signaling pathway regulates cell proliferation, apoptosis, stem cell self-renewal, and differentiation in a context-dependent fashion both during embryonic development and in adult tissue homeostasis. Consistent with its pleiotropic physiological role, unproper activation o...

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Detalles Bibliográficos
Autores principales:	Zhdanovskaya, Nadezda, Firrincieli, Mariarosaria, Lazzari, Sara, Pace, Eleonora, Scribani Rossi, Pietro, Felli, Maria Pia, Talora, Claudio, Screpanti, Isabella, Palermo, Rocco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533696/ https://www.ncbi.nlm.nih.gov/pubmed/34680255 http://dx.doi.org/10.3390/cancers13205106

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