CDKN2A-Mutated Pancreatic Ductal Organoids from Induced Pluripotent Stem Cells to Model a Cancer Predisposition Syndrome

SIMPLE SUMMARY: The mutational landscape of pancreatic ductal adenocarcinoma has been delineated in large clinical studies. Such retrospective characterization, however, is limited to late stages of the disease, and exploring the complexity of carcinogenic routes is in its infancy. Here, we provide...

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Detalles Bibliográficos
Autores principales: Merkle, Jessica, Breunig, Markus, Schmid, Maximilian, Allgöwer, Chantal, Krüger, Jana, Melzer, Michael K., Bens, Susanne, Siebert, Reiner, Perkhofer, Lukas, Azoitei, Ninel, Seufferlein, Thomas, Heller, Sandra, Meier, Matthias, Müller, Martin, Kleger, Alexander, Hohwieler, Meike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533699/
https://www.ncbi.nlm.nih.gov/pubmed/34680288
http://dx.doi.org/10.3390/cancers13205139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533699/
https://www.ncbi.nlm.nih.gov/pubmed/34680288
http://dx.doi.org/10.3390/cancers13205139

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