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Plasma Membrane and Organellar Targets of STIM1 for Intracellular Calcium Handling in Health and Neurodegenerative Diseases

Located at the level of the endoplasmic reticulum (ER) membrane, stromal interacting molecule 1 (STIM1) undergoes a complex conformational rearrangement after depletion of ER luminal Ca(2+). Then, STIM1 translocates into discrete ER-plasma membrane (PM) junctions where it directly interacts with and...

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Detalles Bibliográficos
Autores principales: Tedeschi, Valentina, La Russa, Daniele, Franco, Cristina, Vinciguerra, Antonio, Amantea, Diana, Secondo, Agnese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533710/
https://www.ncbi.nlm.nih.gov/pubmed/34685498
http://dx.doi.org/10.3390/cells10102518