Caspase-Dependent HMGB1 Release from Macrophages Participates in Peripheral Neuropathy Caused by Bortezomib, a Proteasome-Inhibiting Chemotherapeutic Agent, in Mice

Given the role of macrophage-derived high mobility group box 1 (HMGB1) in chemotherapy-induced peripheral neuropathy (CIPN) caused by paclitaxel, we analyzed the role of HMGB1 and macrophages in the CIPN caused by bortezomib, a proteasome-inhibiting chemotherapeutic agent used for the treatment of m...

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Detalles Bibliográficos
Autores principales: Tsubota, Maho, Miyazaki, Takaya, Ikeda, Yuya, Hayashi, Yusuke, Aokiba, Yui, Tomita, Shiori, Sekiguchi, Fumiko, Wang, Dengli, Nishibori, Masahiro, Kawabata, Atsufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533714/
https://www.ncbi.nlm.nih.gov/pubmed/34685531
http://dx.doi.org/10.3390/cells10102550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533714/
https://www.ncbi.nlm.nih.gov/pubmed/34685531
http://dx.doi.org/10.3390/cells10102550

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