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Caspase-Dependent HMGB1 Release from Macrophages Participates in Peripheral Neuropathy Caused by Bortezomib, a Proteasome-Inhibiting Chemotherapeutic Agent, in Mice
Given the role of macrophage-derived high mobility group box 1 (HMGB1) in chemotherapy-induced peripheral neuropathy (CIPN) caused by paclitaxel, we analyzed the role of HMGB1 and macrophages in the CIPN caused by bortezomib, a proteasome-inhibiting chemotherapeutic agent used for the treatment of m...
Autores principales: | Tsubota, Maho, Miyazaki, Takaya, Ikeda, Yuya, Hayashi, Yusuke, Aokiba, Yui, Tomita, Shiori, Sekiguchi, Fumiko, Wang, Dengli, Nishibori, Masahiro, Kawabata, Atsufumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533714/ https://www.ncbi.nlm.nih.gov/pubmed/34685531 http://dx.doi.org/10.3390/cells10102550 |
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