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Treatment with Autophagy Inducer Trehalose Alleviates Memory and Behavioral Impairments and Neuroinflammatory Brain Processes in db/db Mice

Autophagy attenuation has been found in neurodegenerative diseases, aging, diabetes mellitus, and atherosclerosis. In experimental models of neurodegenerative diseases, the correction of autophagy in the brain reverses neuronal and behavioral deficits and hence seems to be a promising therapy for ne...

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Detalles Bibliográficos
Autores principales: Korolenko, Tatiana A., Dubrovina, Nina I., Ovsyukova, Marina V., Bgatova, Nataliya P., Tenditnik, Michael V., Pupyshev, Alexander B., Akopyan, Anna A., Goncharova, Natalya V., Lin, Chih-Li, Zavjalov, Evgeny L., Tikhonova, Maria A., Amstislavskaya, Tamara G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533743/
https://www.ncbi.nlm.nih.gov/pubmed/34685538
http://dx.doi.org/10.3390/cells10102557