Characterization of Microtubule Destabilizing Drugs: A Quantitative Cell-Based Assay That Bridges the Gap between Tubulin Based- and Cytotoxicity Assays

SIMPLE SUMMARY: The characterization of new microtubule depolymerizing agents relies mainly on purified tubulin assays in vitro and on cytotoxicity tests. However, the relationship between the in vitro effects of drugs and their effect on cell viability may not be direct. Here, we have systematicall...

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Detalles Bibliográficos
Autores principales: Laisne, Marie-Catherine, Michallet, Sophie, Lafanechère, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533752/
https://www.ncbi.nlm.nih.gov/pubmed/34680374
http://dx.doi.org/10.3390/cancers13205226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533752/
https://www.ncbi.nlm.nih.gov/pubmed/34680374
http://dx.doi.org/10.3390/cancers13205226

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