Combinatorial Effect of PLK1 Inhibition with Temozolomide and Radiation in Glioblastoma

SIMPLE SUMMARY: There is a critical need to identify readily translatable adjuncts to potentiate the dismal median survivals of only 15–20 months in glioblastoma (GBM) patients after standard of care, i.e., concurrent Temozolomide (TMZ) and radiation (XRT) therapy. Here we demonstrated that the Polo...

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Detalles Bibliográficos
Autores principales: Pandey, Arvind, Tripathi, Satyendra C., Mai, Junhua, Hanash, Samir M., Shen, Haifa, Mitra, Sankar, Rostomily, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533781/
https://www.ncbi.nlm.nih.gov/pubmed/34680264
http://dx.doi.org/10.3390/cancers13205114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533781/
https://www.ncbi.nlm.nih.gov/pubmed/34680264
http://dx.doi.org/10.3390/cancers13205114

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