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The Oncogene MYCN Modulates Glycolytic and Invasive Genes to Enhance Cell Viability and Migration in Human Retinoblastoma
SIMPLE SUMMARY: Retinoblastoma (RB) is a cancer in children, caused by loss of function of RB1 gene. Additional factors such as increase in gene copy numbers of oncogenes MYCN, MDM4 and E2F3 contribute to RB pathogenesis, though their mechanism(s) are not completely understood. We sought to explain...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533785/ https://www.ncbi.nlm.nih.gov/pubmed/34680394 http://dx.doi.org/10.3390/cancers13205248 |