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The Oncogene MYCN Modulates Glycolytic and Invasive Genes to Enhance Cell Viability and Migration in Human Retinoblastoma

SIMPLE SUMMARY: Retinoblastoma (RB) is a cancer in children, caused by loss of function of RB1 gene. Additional factors such as increase in gene copy numbers of oncogenes MYCN, MDM4 and E2F3 contribute to RB pathogenesis, though their mechanism(s) are not completely understood. We sought to explain...

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Detalles Bibliográficos
Autores principales: Sradhanjali, Swatishree, Rout, Padmalochan, Tripathy, Devjyoti, Kaliki, Swathi, Rath, Suryasnata, Modak, Rahul, Mittal, Ruchi, Chowdary, Tirumala Kumar, Reddy, Mamatha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533785/
https://www.ncbi.nlm.nih.gov/pubmed/34680394
http://dx.doi.org/10.3390/cancers13205248