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The Effect of a Histone Deacetylase Inhibitor (AR-42) and Zoledronic Acid on Adult T-Cell Leukemia/Lymphoma Osteolytic Bone Tumors

SIMPLE SUMMARY: Adult T-cell leukemia (ATL) Leukemia is an aggressive, peripheral blood (T-cell) neoplasm associated with human T-cell leukemia virus type 1 (HTLV-1) infection. Recent studies have implicated dysregulated histone deacetylases in ATL pathogenesis. ATL modulates the bone microenvironme...

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Detalles Bibliográficos
Autores principales: Elshafae, Said M., Kohart, Nicole A., Breitbach, Justin T., Hildreth, Blake E., Rosol, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533796/
https://www.ncbi.nlm.nih.gov/pubmed/34680215
http://dx.doi.org/10.3390/cancers13205066