Cargando…
The Effect of a Histone Deacetylase Inhibitor (AR-42) and Zoledronic Acid on Adult T-Cell Leukemia/Lymphoma Osteolytic Bone Tumors
SIMPLE SUMMARY: Adult T-cell leukemia (ATL) Leukemia is an aggressive, peripheral blood (T-cell) neoplasm associated with human T-cell leukemia virus type 1 (HTLV-1) infection. Recent studies have implicated dysregulated histone deacetylases in ATL pathogenesis. ATL modulates the bone microenvironme...
Autores principales: | Elshafae, Said M., Kohart, Nicole A., Breitbach, Justin T., Hildreth, Blake E., Rosol, Thomas J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533796/ https://www.ncbi.nlm.nih.gov/pubmed/34680215 http://dx.doi.org/10.3390/cancers13205066 |
Ejemplares similares
-
Animal Models of Cancer-Associated Hypercalcemia
por: Kohart, Nicole A., et al.
Publicado: (2017) -
Mouse model recapitulates the phenotypic heterogeneity of human adult T-cell leukemia/lymphoma in bone
por: Kohart, Nicole A., et al.
Publicado: (2019) -
Selective Activity of the Histone Deacetylase Inhibitor AR-42 against Leukemia Stem Cells: A Novel Potential Strategy in Acute Myelogenous Leukemia
por: Guzman, Monica L., et al.
Publicado: (2014) -
Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice
por: Chua, Ming Jang, et al.
Publicado: (2021) -
Effect of Dickkopf-1 (Dkk-1) and SP600125, a JNK Inhibitor, on Wnt Signaling in Canine Prostate Cancer Growth and Bone Metastases
por: Supsavhad, Wachiraphan, et al.
Publicado: (2021)