Involvement of Kynurenine Pathway in Hepatocellular Carcinoma

SIMPLE SUMMARY: The kynurenine pathway (KP) is a biochemical pathway that synthesizes the vital coenzyme, nicotinamide adenine dinucleotide (NAD(+)). In cancer, the KP is significantly activated, leading to tryptophan depletion and the production of downstream metabolites, which skews the immune res...

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Shivani, Gilot, David, Ahn, Seong Beom, Lam, Vincent, Shin, Joo-Shik, Guillemin, Gilles Jackie, Heng, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533819/
https://www.ncbi.nlm.nih.gov/pubmed/34680327
http://dx.doi.org/10.3390/cancers13205180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533819/
https://www.ncbi.nlm.nih.gov/pubmed/34680327
http://dx.doi.org/10.3390/cancers13205180

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