Cargando…

Involvement of Kynurenine Pathway in Hepatocellular Carcinoma

SIMPLE SUMMARY: The kynurenine pathway (KP) is a biochemical pathway that synthesizes the vital coenzyme, nicotinamide adenine dinucleotide (NAD(+)). In cancer, the KP is significantly activated, leading to tryptophan depletion and the production of downstream metabolites, which skews the immune res...

Descripción completa

Detalles Bibliográficos
Autores principales:	Krishnamurthy, Shivani, Gilot, David, Ahn, Seong Beom, Lam, Vincent, Shin, Joo-Shik, Guillemin, Gilles Jackie, Heng, Benjamin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533819/ https://www.ncbi.nlm.nih.gov/pubmed/34680327 http://dx.doi.org/10.3390/cancers13205180

Ejemplares similares

Involvement of the kynurenine pathway in breast cancer: updates on clinical research and trials
por: Girithar, Hemaasri-Neya, et al.
Publicado: (2023)

The kynurenine pathway in traumatic brain injuries and concussion
por: Dehhaghi, Mona, et al.
Publicado: (2023)

The Involvement of Neuroinflammation and Kynurenine Pathway in Parkinson's Disease
por: Zinger, Anna, et al.
Publicado: (2011)

Kynurenine and Tetrahydrobiopterin Pathways Crosstalk in Pain Hypersensitivity
por: Staats Pires, Ananda, et al.
Publicado: (2020)

Involvement of the Kynurenine Pathway in Human Glioma Pathophysiology
por: Adams, Seray, et al.
Publicado: (2014)

Kynurenine Pathway Metabolism is Involved in the Maintenance of the Intracellular NAD(+) Concentration in Human Primary Astrocytes
por: Grant, Ross, et al.
Publicado: (2010)

Understanding the role of the kynurenine pathway in human breast cancer immunobiology
por: Heng, Benjamin, et al.
Publicado: (2015)

The Gut Microbiota, Kynurenine Pathway, and Immune System Interaction in the Development of Brain Cancer
por: Dehhaghi, Mona, et al.
Publicado: (2020)

Prophylactic and Therapeutic Effect of Kynurenine for Experimental Autoimmune Encephalomyelitis (EAE) Disease
por: Sundaram, Gayathri, et al.
Publicado: (2022)

The Kynurenine Pathway in Stem Cell Biology
por: Jones, Simon P., et al.
Publicado: (2013)

Kynurenine Pathway Metabolites in Humans: Disease and Healthy States
por: Chen, Yiquan, et al.
Publicado: (2009)

Kynurenine Pathway Metabolites as Biomarkers for Amyotrophic Lateral Sclerosis
por: Tan, Vanessa X., et al.
Publicado: (2019)

The Role of Kynurenine Pathway and NAD(+) Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
por: Dehhaghi, Mona, et al.
Publicado: (2022)

Understanding the Roles of the Kynurenine Pathway in Multiple Sclerosis Progression
por: Lim, Chai K., et al.
Publicado: (2010)

Characterization of the Kynurenine Pathway and Quinolinic Acid Production in Macaque Macrophages
por: Lim, Chai K., et al.
Publicado: (2013)

Major Developments in the Design of Inhibitors along the Kynurenine Pathway
por: Jacobs, Kelly R., et al.
Publicado: (2017)

Kynurenine Pathway in Skin Cells: Implications for UV-Induced Skin Damage
por: Sheipouri, Diba, et al.
Publicado: (2012)

Effects of stress associated with academic examination on the kynurenine pathway profile in healthy students
por: Myint, Kyaimon, et al.
Publicado: (2021)

The kynurenine pathway is involved in bacterial meningitis
por: Coutinho, Leonam G, et al.
Publicado: (2014)

The Involvement of Kynurenine Pathway in Neurodegenerative Diseases
por: Martins, Lais B., et al.
Publicado: (2023)

Development of a translational inflammation panel for the quantification of cerebrospinal fluid Pterin, Tryptophan-Kynurenine and Nitric oxide pathway metabolites
por: Yan, Jingya, et al.
Publicado: (2022)

Temporal Profile of Kynurenine Pathway Metabolites in a Rodent Model of Autosomal Recessive Polycystic Kidney Disease
por: Pires, Ananda Staats, et al.
Publicado: (2022)

Kynurenine pathway modulation reverses the experimental autoimmune encephalomyelitis mouse disease progression
por: Sundaram, Gayathri, et al.
Publicado: (2020)

Effects of Kynurenine Pathway Inhibition on NAD(+) Metabolism and Cell Viability in Human Primary Astrocytes and Neurons
por: Braidy, Nady, et al.
Publicado: (2011)

Neurological Infection, Kynurenine Pathway, and Parasitic Infection by Neospora caninum
por: Del’Arco, Ana Elisa, et al.
Publicado: (2022)

Editorial: Multiple Implications of the Kynurenine Pathway in Inflammatory Diseases: Diagnostic and Therapeutic Applications
por: Mándi, Yvette, et al.
Publicado: (2022)

Could the kynurenine pathway be the key missing piece of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) complex puzzle?
por: Kavyani, Bahar, et al.
Publicado: (2022)

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans
por: Yan, Edwin B., et al.
Publicado: (2015)

Sodium Butyrate and Indole-3-propionic Acid Prevent the Increase of Cytokines and Kynurenine Levels in LPS-induced Human Primary Astrocytes
por: Garcez, Michelle L, et al.
Publicado: (2020)

The Kynurenine Pathway and Kynurenine 3-Monooxygenase Inhibitors
por: Hughes, Tamera D., et al.
Publicado: (2022)

Microorganisms, Tryptophan Metabolism, and Kynurenine Pathway: A Complex Interconnected Loop Influencing Human Health Status
por: Dehhaghi, Mona, et al.
Publicado: (2019)

The kynurenine pathway relates to post‐acute COVID‐19 objective cognitive impairment and PASC
por: Cysique, Lucette A., et al.
Publicado: (2023)

Differential kynurenine pathway metabolism in highly metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression
por: Heng, Benjamin, et al.
Publicado: (2020)

The Plasma [Kynurenine]/[Tryptophan] Ratio and Indoleamine 2,3-Dioxygenase: Time for Appraisal
por: Badawy, Abdulla A-B, et al.
Publicado: (2019)

Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression
por: Lim, Chai K., et al.
Publicado: (2017)

The Tryptophan and Kynurenine Pathway Involved in the Development of Immune-Related Diseases
por: Tsuji, Ai, et al.
Publicado: (2023)

Melatonin ameliorates disease severity in a mouse model of multiple sclerosis by modulating the kynurenine pathway
por: Jand, Yahya, et al.
Publicado: (2022)

Current Evidence for a Role of the Kynurenine Pathway of Tryptophan Metabolism in Multiple Sclerosis
por: Lovelace, Michael D., et al.
Publicado: (2016)

Effects of Kynurenine Pathway Metabolites on Intracellular NAD(+) Synthesis and Cell Death in Human Primary Astrocytes and Neurons
por: Braidy, Nady, et al.
Publicado: (2009)

Modulation of Enzyme Activity in the Kynurenine Pathway by Kynurenine Monooxygenase Inhibition
por: Phillips, Robert S., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5me8pnpb6on003hj3ocage5u8r