Unraveling the Multifaceted Nature of CD8 T Cell Exhaustion Provides the Molecular Basis for Therapeutic T Cell Reconstitution in Chronic Hepatitis B and C

In chronic hepatitis B and C virus infections persistently elevated antigen levels drive CD8+ T cells toward a peculiar differentiation state known as T cell exhaustion, which poses crucial constraints to antiviral immunity. Available evidence indicates that T cell exhaustion is associated with a se...

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Detalles Bibliográficos
Autores principales: Barili, Valeria, Vecchi, Andrea, Rossi, Marzia, Montali, Ilaria, Tiezzi, Camilla, Penna, Amalia, Laccabue, Diletta, Missale, Gabriele, Fisicaro, Paola, Boni, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533840/
https://www.ncbi.nlm.nih.gov/pubmed/34685543
http://dx.doi.org/10.3390/cells10102563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533840/
https://www.ncbi.nlm.nih.gov/pubmed/34685543
http://dx.doi.org/10.3390/cells10102563

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