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DNA Fingerprint Analysis of Raman Spectra Captures Global Genomic Alterations in Imatinib-Resistant Chronic Myeloid Leukemia: A Potential Single Assay for Screening Imatinib Resistance

Monitoring the development of resistance to the tyrosine kinase inhibitor (TKI) imatinib in chronic myeloid leukemia (CML) patients in the initial chronic phase (CP) is crucial for limiting the progression of unresponsive patients to terminal phase of blast crisis (BC). This study for the first time...

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Detalles Bibliográficos
Autores principales: Mojidra, Rahul, Hole, Arti, Iwasaki, Keita, Noothalapati, Hemanth, Yamamoto, Tatsuyuki, C, Murali Krishna, Govekar, Rukmini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533852/
https://www.ncbi.nlm.nih.gov/pubmed/34685486
http://dx.doi.org/10.3390/cells10102506