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TGFβ Signaling in the Pancreatic Tumor Microenvironment

SIMPLE SUMMARY: There is currently no effective treatment for patients with advanced pancreatic ductal adenocarcinoma (PDAC). Transforming Growth Factor β (TGFβ) signaling has been implicated in several hallmark features of PDAC pathobiology, and TGFβ inhibitors are beginning to show promise in the...

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Detalles Bibliográficos
Autores principales: Principe, Daniel R., Timbers, Kaytlin E., Atia, Luke G., Koch, Regina M., Rana, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533869/
https://www.ncbi.nlm.nih.gov/pubmed/34680235
http://dx.doi.org/10.3390/cancers13205086