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Connexin Hemichannel Activation by S-Nitrosoglutathione Synergizes Strongly with Photodynamic Therapy Potentiating Anti-Tumor Bystander Killing

SIMPLE SUMMARY: Bystander effects depend on direct cell-cell communication and/or paracrine signaling mediated by the release of soluble factors into the extracellular environment and may greatly influence therapy outcome. Although the limited data available suggest a role for intercellular gap junc...

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Detalles Bibliográficos
Autores principales: Nardin, Chiara, Peres, Chiara, Putti, Sabrina, Orsini, Tiziana, Colussi, Claudia, Mazzarda, Flavia, Raspa, Marcello, Scavizzi, Ferdinando, Salvatore, Anna Maria, Chiani, Francesco, Tettey-Matey, Abraham, Kuang, Yuanyuan, Yang, Guang, Retamal, Mauricio A., Mammano, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533914/
https://www.ncbi.nlm.nih.gov/pubmed/34680212
http://dx.doi.org/10.3390/cancers13205062