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PCNA Ubiquitylation: Instructive or Permissive to DNA Damage Tolerance Pathways?
DNA lesions escaping from repair often block the DNA replicative polymerases required for DNA replication and are handled during the S/G2 phases by the DNA damage tolerance (DDT) mechanisms, which include the error-prone translesion synthesis (TLS) and the error-free template switching (TS) pathways...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533919/ https://www.ncbi.nlm.nih.gov/pubmed/34680175 http://dx.doi.org/10.3390/biom11101543 |