Cargando…
PCNA Ubiquitylation: Instructive or Permissive to DNA Damage Tolerance Pathways?
DNA lesions escaping from repair often block the DNA replicative polymerases required for DNA replication and are handled during the S/G2 phases by the DNA damage tolerance (DDT) mechanisms, which include the error-prone translesion synthesis (TLS) and the error-free template switching (TS) pathways...
Autores principales: | Che, Jun, Hong, Xin, Rao, Hai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533919/ https://www.ncbi.nlm.nih.gov/pubmed/34680175 http://dx.doi.org/10.3390/biom11101543 |
Ejemplares similares
-
Control of DNA Damage Bypass by Ubiquitylation of PCNA
por: Ripley, Brittany M., et al.
Publicado: (2020) -
Avidity-based biosensors for ubiquitylated PCNA reveal choreography of DNA damage bypass
por: Yakoub, George, et al.
Publicado: (2023) -
Reversal of PCNA Ubiquitylation by Ubp10 in Saccharomyces cerevisiae
por: Gallego-Sánchez, Alfonso, et al.
Publicado: (2012) -
PCNA ubiquitylation ensures timely completion of unperturbed DNA replication in fission yeast
por: Daigaku, Yasukazu, et al.
Publicado: (2017) -
Cryo-EM structure of human Pol κ bound to DNA and mono-ubiquitylated PCNA
por: Lancey, Claudia, et al.
Publicado: (2021)