BMP-7 Attenuates Inflammation-Induced Pyroptosis and Improves Cardiac Repair in Diabetic Cardiomyopathy

In the present study, we investigated a novel signaling target in diabetic cardiomyopathy where inflammation induces caspase-1-dependent cell death, pyroptosis, involving Nek7-GBP5 activators to activate the NLRP3 inflammasome, destabilizes cardiac structure and neovascularization. Furthermore, we e...

Descripción completa

Detalles Bibliográficos
Autores principales: Elmadbouh, Ibrahim, Singla, Dinender K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533936/
https://www.ncbi.nlm.nih.gov/pubmed/34685620
http://dx.doi.org/10.3390/cells10102640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533936/
https://www.ncbi.nlm.nih.gov/pubmed/34685620
http://dx.doi.org/10.3390/cells10102640

Ejemplares similares