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A Core Transcription Regulatory Circuitry Defining Microglia Cell Identity Inferred from the Reanalysis of Multiple Human Microglia Differentiation Protocols

Microglia, the immune cells in the brain involved in both homeostasis and injury/infection control, play a predominant role in neurodegenerative diseases. In vivo studies on microglia are limited due to the requirement of surgical intervention, which can lead to the destruction of the tissues. Over...

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Detalles Bibliográficos
Autores principales: Aubert, Antoine, Stüder, François, Colombo, Bruno Maria, Mendoza-Parra, Marco Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533937/
https://www.ncbi.nlm.nih.gov/pubmed/34679401
http://dx.doi.org/10.3390/brainsci11101338