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Dabigatran Etexilate Induces Cytotoxicity in Rat Gastric Epithelial Cell Line via Mitochondrial Reactive Oxygen Species Production

Dabigatran is a novel oral anticoagulant that directly inhibits free and fibrin-bound thrombins and exerts rapid and predictable anticoagulant effects. While the use of this reagent has been associated with an increased risk of gastrointestinal bleeding, the reason why dabigatran use increases gastr...

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Detalles Bibliográficos
Autores principales: Kurokawa, Hiromi, Taninaka, Atsushi, Shigekawa, Hidemi, Matsui, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533938/
https://www.ncbi.nlm.nih.gov/pubmed/34685491
http://dx.doi.org/10.3390/cells10102508