Pirfenidone Reduces Epithelial–Mesenchymal Transition and Spheroid Formation in Breast Carcinoma through Targeting Cancer-Associated Fibroblasts (CAFs)

SIMPLE SUMMARY: Cancer-associated fibroblasts (CAFs) stimulate phenotypic transformation and acquisition of stemness in carcinoma cells. Targeting CAF-derived cytokines may suppress initiation of these events. This study aimed to show the inhibitory effects of pirfenidone on phenotypic transformatio...

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Detalles Bibliográficos
Autores principales: Es, Hamidreza Aboulkheyr, Cox, Thomas R, Sarafraz-Yazdi, Ehsan, Thiery, Jean Paul, Warkiani, Majid Ebrahimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533995/
https://www.ncbi.nlm.nih.gov/pubmed/34680267
http://dx.doi.org/10.3390/cancers13205118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533995/
https://www.ncbi.nlm.nih.gov/pubmed/34680267
http://dx.doi.org/10.3390/cancers13205118

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