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Investigation of Neurodevelopmental Deficits of 22 q11.2 Deletion Syndrome with a Patient-iPSC-Derived Blood–Brain Barrier Model

The blood–brain barrier (BBB) is important in the normal functioning of the central nervous system. An altered BBB has been described in various neuropsychiatric disorders, including schizophrenia. However, the cellular and molecular mechanisms of such alterations remain unclear. Here, we investigat...

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Detalles Bibliográficos
Autores principales: Li, Yunfei, Xia, Yifan, Zhu, Huixiang, Luu, Eric, Huang, Guangyao, Sun, Yan, Sun, Kevin, Markx, Sander, Leong, Kam W., Xu, Bin, Fu, Bingmei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534009/
https://www.ncbi.nlm.nih.gov/pubmed/34685556
http://dx.doi.org/10.3390/cells10102576