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Mitochondrial Dysfunction, Protein Misfolding and Neuroinflammation in Parkinson’s Disease: Roads to Biomarker Discovery

Parkinson’s Disease (PD) is a highly prevalent neurodegenerative disease among older adults. PD neuropathology is marked by the progressive loss of the dopaminergic neurons of the substantia nigra pars compacta and the widespread accumulation of misfolded intracellular α-synuclein (α-syn). Genetic m...

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Detalles Bibliográficos
Autores principales: Picca, Anna, Guerra, Flora, Calvani, Riccardo, Romano, Roberta, Coelho-Júnior, Hélio José, Bucci, Cecilia, Marzetti, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534011/
https://www.ncbi.nlm.nih.gov/pubmed/34680141
http://dx.doi.org/10.3390/biom11101508