Oxytocin Is a Positive Allosteric Modulator of κ-Opioid Receptors but Not δ-Opioid Receptors in the G Protein Signaling Pathway

Oxytocin (OT) influences various physiological functions such as uterine contractions, maternal/social behavior, and analgesia. Opioid signaling pathways are involved in one of the analgesic mechanisms of OT. We previously showed that OT acts as a positive allosteric modulator (PAM) and enhances μ-o...

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Detalles Bibliográficos
Autores principales: Miyano, Kanako, Yoshida, Yuki, Hirayama, Shigeto, Takahashi, Hideki, Ono, Haruka, Meguro, Yoshiyuki, Manabe, Sei, Komatsu, Akane, Nonaka, Miki, Mizuguchi, Takaaki, Fujii, Hideaki, Higami, Yoshikazu, Narita, Minoru, Uezono, Yasuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534029/
https://www.ncbi.nlm.nih.gov/pubmed/34685631
http://dx.doi.org/10.3390/cells10102651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534029/
https://www.ncbi.nlm.nih.gov/pubmed/34685631
http://dx.doi.org/10.3390/cells10102651

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