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Oxytocin Is a Positive Allosteric Modulator of κ-Opioid Receptors but Not δ-Opioid Receptors in the G Protein Signaling Pathway
Oxytocin (OT) influences various physiological functions such as uterine contractions, maternal/social behavior, and analgesia. Opioid signaling pathways are involved in one of the analgesic mechanisms of OT. We previously showed that OT acts as a positive allosteric modulator (PAM) and enhances μ-o...
Autores principales: | Miyano, Kanako, Yoshida, Yuki, Hirayama, Shigeto, Takahashi, Hideki, Ono, Haruka, Meguro, Yoshiyuki, Manabe, Sei, Komatsu, Akane, Nonaka, Miki, Mizuguchi, Takaaki, Fujii, Hideaki, Higami, Yoshikazu, Narita, Minoru, Uezono, Yasuhito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534029/ https://www.ncbi.nlm.nih.gov/pubmed/34685631 http://dx.doi.org/10.3390/cells10102651 |
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