Resveratrol Treatment in Human Parkin-Mutant Fibroblasts Modulates cAMP and Calcium Homeostasis Regulating the Expression of Mitochondria-Associated Membranes Resident Proteins

Parkin plays an important role in ensuring efficient mitochondrial function and calcium homeostasis. Parkin-mutant human fibroblasts, with defective oxidative phosphorylation activity, showed high basal cAMP level likely ascribed to increased activity/expression of soluble adenylyl cyclase and/or lo...

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Detalles Bibliográficos
Autores principales: Signorile, Anna, Ferretta, Anna, Pacelli, Consiglia, Capitanio, Nazzareno, Tanzarella, Paola, Matrella, Maria Laura, Valletti, Alessio, De Rasmo, Domenico, Cocco, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534032/
https://www.ncbi.nlm.nih.gov/pubmed/34680144
http://dx.doi.org/10.3390/biom11101511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534032/
https://www.ncbi.nlm.nih.gov/pubmed/34680144
http://dx.doi.org/10.3390/biom11101511

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