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Resveratrol Treatment in Human Parkin-Mutant Fibroblasts Modulates cAMP and Calcium Homeostasis Regulating the Expression of Mitochondria-Associated Membranes Resident Proteins
Parkin plays an important role in ensuring efficient mitochondrial function and calcium homeostasis. Parkin-mutant human fibroblasts, with defective oxidative phosphorylation activity, showed high basal cAMP level likely ascribed to increased activity/expression of soluble adenylyl cyclase and/or lo...
Autores principales: | Signorile, Anna, Ferretta, Anna, Pacelli, Consiglia, Capitanio, Nazzareno, Tanzarella, Paola, Matrella, Maria Laura, Valletti, Alessio, De Rasmo, Domenico, Cocco, Tiziana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534032/ https://www.ncbi.nlm.nih.gov/pubmed/34680144 http://dx.doi.org/10.3390/biom11101511 |
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