Hepatocyte Polyploidy: Driver or Gatekeeper of Chronic Liver Diseases

SIMPLE SUMMARY: Polyploidy, a balanced amplification of the genome is a defining feature of the liver. Up to 90% of adult hepatocytes in rodents and around 40% of those in humans are polyploid. The polyploidy of these cells depends on both the DNA content of each nucleus (nuclear ploidy) and the num...

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Detalles Bibliográficos
Autores principales: Donne, Romain, Sangouard, Flora, Celton-Morizur, Séverine, Desdouets, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534039/
https://www.ncbi.nlm.nih.gov/pubmed/34680300
http://dx.doi.org/10.3390/cancers13205151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534039/
https://www.ncbi.nlm.nih.gov/pubmed/34680300
http://dx.doi.org/10.3390/cancers13205151

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