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Hepatocyte Polyploidy: Driver or Gatekeeper of Chronic Liver Diseases
SIMPLE SUMMARY: Polyploidy, a balanced amplification of the genome is a defining feature of the liver. Up to 90% of adult hepatocytes in rodents and around 40% of those in humans are polyploid. The polyploidy of these cells depends on both the DNA content of each nucleus (nuclear ploidy) and the num...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534039/ https://www.ncbi.nlm.nih.gov/pubmed/34680300 http://dx.doi.org/10.3390/cancers13205151 |