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Data Mining of Molecular Simulations Suggest Key Amino Acid Residues for Aggregation, Signaling and Drug Action

Alzheimer’s disease, the most common form of dementia, currently has no cure. There are only temporary treatments that reduce symptoms and the progression of the disease. Alzheimer’s disease is characterized by the prevalence of plaques of aggregated amyloid β (Aβ) peptide. Recent treatments to prev...

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Detalles Bibliográficos
Autores principales: Gurunathan, Vaibhav, Hamre, John, Klimov, Dmitri K., Jafri, Mohsin Saleet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534076/
https://www.ncbi.nlm.nih.gov/pubmed/34680174
http://dx.doi.org/10.3390/biom11101541