The Prevalence of Pathogenic or Likely Pathogenic Germline Variants in a Nationwide Cohort of Young Colorectal Cancer Patients Using a Panel of 18 Genes Associated with Colorectal Cancer

SIMPLE SUMMARY: This study reveals that pathogenic or likely pathogenic germline variants are detected in one fourth of all young patients with colorectal cancer in a nationwide cohort. Immunohistochemistry staining for mismatch repair deficiency is an easy way to detect Lynch syndrome in the young...

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Detalles Bibliográficos
Autores principales: Frostberg, Erik, Petersen, Annabeth Høgh, Bojesen, Anders, Rahr, Hans Bjarke, Lindebjerg, Jan, Rønlund, Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534092/
https://www.ncbi.nlm.nih.gov/pubmed/34680242
http://dx.doi.org/10.3390/cancers13205094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534092/
https://www.ncbi.nlm.nih.gov/pubmed/34680242
http://dx.doi.org/10.3390/cancers13205094

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