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NanoHIV: A Bioinformatics Pipeline for Producing Accurate, Near Full-Length HIV Proviral Genomes Sequenced Using the Oxford Nanopore Technology

HIV-1 proviral single-genome sequencing by limiting-dilution polymerase chain reaction (PCR) amplification is important for differentiating the sequence-intact from defective proviruses that persist during antiretroviral therapy (ART). Intact proviruses may rebound if ART is interrupted and are the...

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Detalles Bibliográficos
Autores principales: Wright, Imogen A., Delaney, Kayla E., Katusiime, Mary Grace K., Botha, Johannes C., Engelbrecht, Susan, Kearney, Mary F., van Zyl, Gert U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534097/
https://www.ncbi.nlm.nih.gov/pubmed/34685559
http://dx.doi.org/10.3390/cells10102577