The Genetic Makeup of Myeloproliferative Neoplasms: Role of Germline Variants in Defining Disease Risk, Phenotypic Diversity and Outcome

Myeloproliferative neoplasms are hematologic malignancies typified by a substantial heritable component. Germline variants may affect the risk of developing a MPN, as documented by GWAS studies on large patient cohorts. In addition, once the MPN occurred, inherited host genetic factors can be respon...

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Detalles Bibliográficos
Autores principales: Masselli, Elena, Pozzi, Giulia, Carubbi, Cecilia, Vitale, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534117/
https://www.ncbi.nlm.nih.gov/pubmed/34685575
http://dx.doi.org/10.3390/cells10102597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534117/
https://www.ncbi.nlm.nih.gov/pubmed/34685575
http://dx.doi.org/10.3390/cells10102597

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