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Partial Ablation of Non-Myogenic Progenitor Cells as a Therapeutic Approach to Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD), caused by the loss of dystrophin, remains incurable. Reduction in muscle regeneration with DMD is associated with the accumulation of fibroadipogenic progenitors (FAPs) differentiating into myofibroblasts and leading to a buildup of the collagenous tissue aggravati...

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Detalles Bibliográficos
Autores principales: Gao, Zhanguo, Lu, Aiping, Daquinag, Alexes C., Yu, Yongmei, Huard, Matthieu, Tseng, Chieh, Gao, Xueqin, Huard, Johnny, Kolonin, Mikhail G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534118/
https://www.ncbi.nlm.nih.gov/pubmed/34680151
http://dx.doi.org/10.3390/biom11101519