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Lamin B1 Accumulation’s Effects on Autosomal Dominant Leukodystrophy (ADLD): Induction of Reactivity in the Astrocytes

Autosomal dominant leukodystrophy (ADLD) is an extremely rare and fatal neurodegenerative disease due to the overexpression of the nuclear lamina component Lamin B1. Many aspects of the pathology still remain unrevealed. This work highlights the effect of Lamin B1 accumulation on different cellular...

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Detalles Bibliográficos
Autores principales: Ratti, Stefano, Rusciano, Isabella, Mongiorgi, Sara, Neri, Irene, Cappellini, Alessandra, Cortelli, Pietro, Suh, Pann-Ghill, McCubrey, James A., Manzoli, Lucia, Cocco, Lucio, Ramazzotti, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534128/
https://www.ncbi.nlm.nih.gov/pubmed/34685544
http://dx.doi.org/10.3390/cells10102566