Reversal of ABCG2/BCRP-Mediated Multidrug Resistance by 5,3′,5′-Trihydroxy-3,6,7,4′-Tetramethoxyflavone Isolated from the Australian Desert Plant Eremophila galeata Chinnock

Multidrug resistance (MDR) is a major challenge in cancer treatment, and the breast cancer resistance protein (BCRP) is an important target in the search for new MDR-reversing drugs. With the aim of discovering new potential BCRP inhibitors, the crude extract of leaves of Eremophila galeata, a plant...

Descripción completa

Detalles Bibliográficos
Autores principales: Petersen, Malene J., Lund, Xamuel L., Semple, Susan J., Buirchell, Bevan, Franzyk, Henrik, Gajhede, Michael, Kongstad, Kenneth T., Stenvang, Jan, Staerk, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534154/
https://www.ncbi.nlm.nih.gov/pubmed/34680166
http://dx.doi.org/10.3390/biom11101534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534154/
https://www.ncbi.nlm.nih.gov/pubmed/34680166
http://dx.doi.org/10.3390/biom11101534

Ejemplares similares