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Reversal of ABCG2/BCRP-Mediated Multidrug Resistance by 5,3′,5′-Trihydroxy-3,6,7,4′-Tetramethoxyflavone Isolated from the Australian Desert Plant Eremophila galeata Chinnock
Multidrug resistance (MDR) is a major challenge in cancer treatment, and the breast cancer resistance protein (BCRP) is an important target in the search for new MDR-reversing drugs. With the aim of discovering new potential BCRP inhibitors, the crude extract of leaves of Eremophila galeata, a plant...
Autores principales: | Petersen, Malene J., Lund, Xamuel L., Semple, Susan J., Buirchell, Bevan, Franzyk, Henrik, Gajhede, Michael, Kongstad, Kenneth T., Stenvang, Jan, Staerk, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534154/ https://www.ncbi.nlm.nih.gov/pubmed/34680166 http://dx.doi.org/10.3390/biom11101534 |
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