Reinspection of a Clinical Proteomics Tumor Analysis Consortium (CPTAC) Dataset with Cloud Computing Reveals Abundant Post-Translational Modifications and Protein Sequence Variants

SIMPLE SUMMARY: We reanalyzed a publicly available breast cancer proteomics dataset consisting of 122 human tumor samples using a scalable cloud computing workflow. By doing so, we were able to search these files against millions of known human sequence variants and hundreds of common post-translati...

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Detalles Bibliográficos
Autores principales: Prakash, Amol, Taylor, Lorne, Varkey, Manu, Hoxie, Nate, Mohammed, Yassene, Goo, Young Ah, Peterman, Scott, Moghekar, Abhay, Yuan, Yuting, Glaros, Trevor, Steele, Joel R., Faridi, Pouya, Parihari, Shashwati, Srivastava, Sanjeeva, Otto, Joseph J., Nyalwidhe, Julius O., Semmes, O. John, Moran, Michael F., Madugundu, Anil, Mun, Dong Gi, Pandey, Akhilesh, Mahoney, Keira E., Shabanowitz, Jeffrey, Saxena, Satya, Orsburn, Benjamin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534219/
https://www.ncbi.nlm.nih.gov/pubmed/34680183
http://dx.doi.org/10.3390/cancers13205034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534219/
https://www.ncbi.nlm.nih.gov/pubmed/34680183
http://dx.doi.org/10.3390/cancers13205034

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