Bile Acids Activate NLRP3 Inflammasome, Promoting Murine Liver Inflammation or Fibrosis in a Cell Type-Specific Manner

Bile acids (BA) as important signaling molecules are considered crucial in development of cholestatic liver injury, but there is limited understanding on the involved cell types and signaling pathways. The aim of this study was to evaluate the inflammatory and fibrotic potential of key BA and the ro...

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Detalles Bibliográficos
Autores principales: Holtmann, Theresa Maria, Inzaugarat, Maria Eugenia, Knorr, Jana, Geisler, Lukas, Schulz, Marten, Bieghs, Veerle, Frissen, Mick, Feldstein, Ariel E., Tacke, Frank, Trautwein, Christian, Wree, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534222/
https://www.ncbi.nlm.nih.gov/pubmed/34685598
http://dx.doi.org/10.3390/cells10102618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534222/
https://www.ncbi.nlm.nih.gov/pubmed/34685598
http://dx.doi.org/10.3390/cells10102618

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