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Bile Acids Activate NLRP3 Inflammasome, Promoting Murine Liver Inflammation or Fibrosis in a Cell Type-Specific Manner
Bile acids (BA) as important signaling molecules are considered crucial in development of cholestatic liver injury, but there is limited understanding on the involved cell types and signaling pathways. The aim of this study was to evaluate the inflammatory and fibrotic potential of key BA and the ro...
Autores principales: | Holtmann, Theresa Maria, Inzaugarat, Maria Eugenia, Knorr, Jana, Geisler, Lukas, Schulz, Marten, Bieghs, Veerle, Frissen, Mick, Feldstein, Ariel E., Tacke, Frank, Trautwein, Christian, Wree, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534222/ https://www.ncbi.nlm.nih.gov/pubmed/34685598 http://dx.doi.org/10.3390/cells10102618 |
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