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Recent Advances in Molecular Diagnostics and Targeted Therapy of Myeloproliferative Neoplasms

SIMPLE SUMMARY: Myeloproliferative neoplasms (MPN) are clonal hematologic malignancies with dysregulated myeloid blood cell production driven by JAK2, calreticulin, and MPL gene mutations. Technological advances have revealed a heterogeneous genomic landscape with additional mutations mainly in epig...

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Detalles Bibliográficos
Autores principales: Stivala, Simona, Meyer, Sara C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534234/
https://www.ncbi.nlm.nih.gov/pubmed/34680185
http://dx.doi.org/10.3390/cancers13205035