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The Many Potential Fates of Non-Canonical Protein Substrates Subject to NEDDylation

Neuronal precursor cell-expressed developmentally down-regulated protein 8 (NEDD8) is a ubiquitin-like protein (UBL) whose canonical function involves binding to, and thus, activating Cullin–Ring finger Ligases (CRLs), one of the largest family of ubiquitin ligases in the eukaryotic cell. However, i...

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Detalles Bibliográficos
Autores principales: Vijayasimha, Kartikeya, Dolan, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534235/
https://www.ncbi.nlm.nih.gov/pubmed/34685640
http://dx.doi.org/10.3390/cells10102660