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Identification of the Novel Tumor Suppressor Role of FOCAD/miR-491-5p to Inhibit Cancer Stemness, Drug Resistance and Metastasis via Regulating RABIF/MMP Signaling in Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) possesses poor prognosis mainly due to development of chemoresistance and lack of effective endocrine or targeted therapies. MiR-491-5p has been found to play a tumor suppressor role in many cancers including breast cancer. However, the precise role of miR-491-5p...

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Detalles Bibliográficos
Autores principales: Huang, Wei-Chieh, Chi, Hsiang-Cheng, Tung, Shiao-Lin, Chen, Po-Ming, Shih, Ya-Chi, Huang, Yi-Ching, Chu, Pei-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534268/
https://www.ncbi.nlm.nih.gov/pubmed/34685504
http://dx.doi.org/10.3390/cells10102524